NephVar
/
Biophysical
/ UMOD
UMOD
CAKUT panel · 640 aa · UniProt
P07911
Protein map — domains / secondary structure / RSA / pLDDT
Helix
Sheet
Loop / coil
pLDDT confidence
Buried (RSA < 0.25)
Exposed (RSA ≥ 0.25)
All secondary structures
Helix
Sheet
Loop / coil
All domains
Beta hairpin
D10C
EGF-like 1
EGF-like 2; calcium-binding
EGF-like 3; calcium-binding
EGF-like 4
Essential for cleavage by HPN
External hydrophobic patch (EHP); regulates polymerization into filaments
Flexible ZP-N/ZP-C linker; important for secretion and polymerization into filaments
Internal hydrophobic patch (IHP)
ZP
ZP-C
ZP-N
Pos
AA
RSA
2° structure
pLDDT
Burial
Domain
No residues match.