NephVar / Molecular Grammars / ARHGAP24

ARHGAP24 RHG24

SRNS panel · 748 aa · UniProt Q8N264 · 2 IDRs · View biophysical profile →
IDR map — colored by GIN molecular grammar cluster
IDR 1 Cluster 17
Residues 332–484 · 152 aa (20.3% of protein) · Min inter-cluster distance: 8.323
Weak positive charge
Sequence
AELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSNAEGLEKTQTTPNGSLQARRSSSLKVSGTKMGTHSVQNGTVRM
Top exceptional features (|z-score| rank)
N Patch: +3.42Frac N: +2.60pos-pos: -2.25Disorder Promoting: -1.64hyd-pos: -1.57Frac Polar: +1.41pol-pos: -1.20Frac Chain Expanding: -1.19
Show all 90 sequence-feature z-scores
FeatureZ-score
pol-pol-1.095
pol-hyd-0.178
pol-pos-1.203
pol-neg+0.000
pol-aro+0.000
pol-ala+0.000
pol-pro+0.000
pol-gly+0.000
hyd-hyd-0.416
hyd-pos-1.575
hyd-neg+0.000
hyd-aro+0.000
hyd-ala+0.000
hyd-pro+0.000
hyd-gly+0.000
pos-pos-2.253
pos-neg+0.000
pos-aro+0.000
pos-ala+0.000
pos-pro+0.000
pos-gly+0.000
neg-neg+0.000
neg-aro+0.000
neg-ala+0.000
neg-pro+0.000
neg-gly+0.000
aro-aro+0.000
aro-ala+0.000
aro-pro+0.000
aro-gly+0.000
ala-ala+0.000
ala-pro+0.000
ala-gly+0.000
pro-pro+0.000
pro-gly+0.000
gly-gly+0.000
Frac A-0.696
Frac C-0.134
Frac D-0.601
Frac E-0.761
Frac F-0.063
Frac G-0.071
Frac H-0.368
Frac I-0.237
Frac K+0.670
Frac L-0.173
Frac M+0.861
Frac N+2.599
Frac P-0.764
Frac Q+0.250
Frac R-0.522
Frac S+0.788
Frac T+0.340
Frac V+0.612
Frac W+0.091
Frac Y-0.609
Frac K+R+0.151
Frac D+E-0.870
Frac Polar+1.413
Frac Aliphatic-0.248
Frac Aromatic-0.387
R/K Ratio-1.005
E/D Ratio-0.117
Frac Chain Expanding-1.194
FCR-0.556
NCPR+0.757
Hydrophobicity-0.056
Disorder Promoting-1.642
Iso point+0.872
PPII-0.756
A Patch-0.265
C Patch-0.009
D Patch-0.178
E Patch-0.349
F Patch-0.012
G Patch-0.259
H Patch-0.077
I Patch-0.011
K Patch-0.253
L Patch-0.096
M Patch-0.026
N Patch+3.422
P Patch-0.447
Q Patch-0.160
R Patch-0.247
S Patch-0.110
T Patch-0.147
V Patch-0.051
Y Patch-0.022
RG Frac-0.130
IDR 2 Cluster 6
Residues 546–650 · 104 aa (13.9% of protein) · Min inter-cluster distance: 1.383
S patches
Sequence
KQSIDSATWSTSSCEISLPENSNSCRSSTTTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVGNSSSNHSALHSLVSS
Top exceptional features (|z-score| rank)
pol-pol: +2.62pol-hyd: +2.34Frac S: +2.02S Patch: +1.58pol-neg: +1.56PPII: -1.54Frac Polar: +1.53Frac C: +1.39
Show all 90 sequence-feature z-scores
FeatureZ-score
pol-pol+2.618
pol-hyd+2.343
pol-pos+0.000
pol-neg+1.556
pol-aro+0.000
pol-ala+0.000
pol-pro+0.000
pol-gly+0.000
hyd-hyd+0.910
hyd-pos+0.000
hyd-neg-0.479
hyd-aro+0.000
hyd-ala+0.000
hyd-pro+0.000
hyd-gly+0.000
pos-pos+0.000
pos-neg+0.000
pos-aro+0.000
pos-ala+0.000
pos-pro+0.000
pos-gly+0.000
neg-neg+0.076
neg-aro+0.000
neg-ala+0.000
neg-pro+0.000
neg-gly+0.000
aro-aro+0.000
aro-ala+0.000
aro-pro+0.000
aro-gly+0.000
ala-ala+0.000
ala-pro+0.000
ala-gly+0.000
pro-pro+0.000
pro-gly+0.000
gly-gly+0.000
Frac A-0.891
Frac C+1.385
Frac D+0.849
Frac E-0.487
Frac F+1.368
Frac G-0.415
Frac H+0.558
Frac I+0.069
Frac K-0.742
Frac L-0.304
Frac M-0.832
Frac N+0.862
Frac P-0.785
Frac Q-0.568
Frac R-0.351
Frac S+2.017
Frac T+0.226
Frac V+0.094
Frac W+0.367
Frac Y-0.039
Frac K+R-0.786
Frac D+E+0.033
Frac Polar+1.532
Frac Aliphatic-1.165
Frac Aromatic+1.027
R/K Ratio+0.598
E/D Ratio-1.040
Frac Chain Expanding-1.133
FCR-0.490
NCPR-0.542
Hydrophobicity+0.302
Disorder Promoting-0.933
Iso point-0.944
PPII-1.539
A Patch-0.265
C Patch-0.009
D Patch-0.178
E Patch-0.349
F Patch-0.012
G Patch-0.259
H Patch-0.077
I Patch-0.011
K Patch-0.253
L Patch-0.096
M Patch-0.026
N Patch-0.076
P Patch-0.447
Q Patch-0.160
R Patch-0.247
S Patch+1.583
T Patch-0.147
V Patch-0.051
Y Patch-0.022
RG Frac-0.130