IDR 1
Cluster 22
Residues 42–1478 · 1436 aa
(85.2% of protein) · Min inter-cluster distance: 57.74
Well-mixed P and G
Note: this region spans the majority of the protein sequence, which may indicate a structured domain (e.g. a collagen triple helix or repetitive fibrous domain) that AlphaFold2 monomer predictions and sequence-based disorder predictors can misclassify as disordered. Interpret this grammar assignment with caution.
Sequence
IKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQ
Top exceptional features (|z-score| rank)
gly-gly: -9.87G Patch: +9.76pro-gly: -8.20hyd-gly: -7.57pol-gly: -6.63Frac G: +3.79P Patch: +3.58hyd-hyd: -2.81
Show all 90 sequence-feature z-scores
| Feature | Z-score |
|---|
| pol-pol | -2.383 |
| pol-hyd | -2.413 |
| pol-pos | +0.000 |
| pol-neg | +0.000 |
| pol-aro | +0.000 |
| pol-ala | +0.000 |
| pol-pro | +1.624 |
| pol-gly | -6.635 |
| hyd-hyd | -2.814 |
| hyd-pos | +0.000 |
| hyd-neg | +0.000 |
| hyd-aro | +0.000 |
| hyd-ala | +0.000 |
| hyd-pro | -1.964 |
| hyd-gly | -7.565 |
| pos-pos | +0.000 |
| pos-neg | +0.000 |
| pos-aro | +0.000 |
| pos-ala | +0.000 |
| pos-pro | +0.000 |
| pos-gly | +0.000 |
| neg-neg | +0.000 |
| neg-aro | +0.000 |
| neg-ala | +0.000 |
| neg-pro | +0.000 |
| neg-gly | +0.000 |
| aro-aro | +0.000 |
| aro-ala | +0.000 |
| aro-pro | +0.000 |
| aro-gly | +0.000 |
| ala-ala | +0.000 |
| ala-pro | +0.000 |
| ala-gly | +0.000 |
| pro-pro | -0.442 |
| pro-gly | -8.199 |
| gly-gly | -9.866 |
| Frac A | -1.101 |
| Frac C | -0.345 |
| Frac D | -0.447 |
| Frac E | -0.810 |
| Frac F | +0.335 |
| Frac G | +3.788 |
| Frac H | -0.646 |
| Frac I | +1.206 |
| Frac K | -0.180 |
| Frac L | +0.154 |
| Frac M | -0.258 |
| Frac N | -0.453 |
| Frac P | +2.120 |
| Frac Q | -0.282 |
| Frac R | -0.959 |
| Frac S | -1.498 |
| Frac T | -0.862 |
| Frac V | -0.802 |
| Frac W | -0.508 |
| Frac Y | -0.444 |
| Frac K+R | -0.774 |
| Frac D+E | -0.834 |
| Frac Polar | +0.455 |
| Frac Aliphatic | -0.941 |
| Frac Aromatic | -0.266 |
| R/K Ratio | -1.236 |
| E/D Ratio | -0.433 |
| Frac Chain Expanding | +0.187 |
| FCR | -1.134 |
| NCPR | +0.121 |
| Hydrophobicity | +0.816 |
| Disorder Promoting | +0.431 |
| Iso point | -0.137 |
| PPII | +1.072 |
| A Patch | -0.265 |
| C Patch | -0.009 |
| D Patch | -0.178 |
| E Patch | -0.248 |
| F Patch | -0.012 |
| G Patch | +9.756 |
| H Patch | -0.077 |
| I Patch | -0.011 |
| K Patch | -0.253 |
| L Patch | -0.096 |
| M Patch | -0.026 |
| N Patch | -0.076 |
| P Patch | +3.579 |
| Q Patch | -0.160 |
| R Patch | -0.247 |
| S Patch | -0.481 |
| T Patch | -0.147 |
| V Patch | -0.051 |
| Y Patch | -0.022 |
| RG Frac | +1.978 |