IDR 1
Cluster 15
Residues 21–1036 · 1015 aa
(80.9% of protein) · Min inter-cluster distance: 4.439
T patches
Note: this region spans the majority of the protein sequence, which may indicate a structured domain (e.g. a collagen triple helix or repetitive fibrous domain) that AlphaFold2 monomer predictions and sequence-based disorder predictors can misclassify as disordered. Interpret this grammar assignment with caution.
Sequence
TGSGHASSTPGGEKETSATQRSSVPSSTEKNAVSMTSSVLSSHSPGSGSSTTQGQDVTLAPATEPASGSAATWGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDNRPALGSTAPPVHNVTSASGSASGSASTLVHNGTSARATTTPASKSTPFSIPSHHSDTPTTLASHSTKTDASSTHHSSVPPLTSSNHSTSPQL
Top exceptional features (|z-score| rank)
ala-ala: -12.89ala-pro: -8.97pol-pol: -5.42pol-ala: -5.17E/D Ratio: -3.58pro-pro: -3.03Disorder Promoting: +2.30Frac T: +2.12
Show all 90 sequence-feature z-scores
| Feature | Z-score |
|---|
| pol-pol | -5.415 |
| pol-hyd | +0.000 |
| pol-pos | +0.000 |
| pol-neg | +0.000 |
| pol-aro | +0.000 |
| pol-ala | -5.173 |
| pol-pro | -2.075 |
| pol-gly | +0.000 |
| hyd-hyd | +0.000 |
| hyd-pos | +0.000 |
| hyd-neg | +0.000 |
| hyd-aro | +0.000 |
| hyd-ala | +0.000 |
| hyd-pro | +0.000 |
| hyd-gly | +0.000 |
| pos-pos | +0.000 |
| pos-neg | +0.000 |
| pos-aro | +0.000 |
| pos-ala | +0.000 |
| pos-pro | +0.000 |
| pos-gly | +0.000 |
| neg-neg | +0.000 |
| neg-aro | +0.000 |
| neg-ala | +0.000 |
| neg-pro | +0.000 |
| neg-gly | +0.000 |
| aro-aro | +0.000 |
| aro-ala | +0.000 |
| aro-pro | +0.000 |
| aro-gly | +0.000 |
| ala-ala | -12.895 |
| ala-pro | -8.972 |
| ala-gly | +0.000 |
| pro-pro | -3.028 |
| pro-gly | +0.000 |
| gly-gly | +0.000 |
| Frac A | +1.924 |
| Frac C | -0.582 |
| Frac D | -0.120 |
| Frac E | -1.294 |
| Frac F | -0.751 |
| Frac G | +0.182 |
| Frac H | +1.025 |
| Frac I | -0.851 |
| Frac K | -0.996 |
| Frac L | -1.455 |
| Frac M | -0.781 |
| Frac N | -0.800 |
| Frac P | +1.540 |
| Frac Q | -1.098 |
| Frac R | -0.445 |
| Frac S | +0.001 |
| Frac T | +2.120 |
| Frac V | +0.597 |
| Frac W | -0.418 |
| Frac Y | -0.609 |
| Frac K+R | -1.038 |
| Frac D+E | -1.049 |
| Frac Polar | +0.500 |
| Frac Aliphatic | +0.626 |
| Frac Aromatic | -1.049 |
| R/K Ratio | +1.991 |
| E/D Ratio | -3.577 |
| Frac Chain Expanding | -0.617 |
| FCR | -1.469 |
| NCPR | +0.110 |
| Hydrophobicity | +1.060 |
| Disorder Promoting | +2.302 |
| Iso point | +0.401 |
| PPII | +0.996 |
| A Patch | -0.265 |
| C Patch | -0.009 |
| D Patch | -0.178 |
| E Patch | -0.349 |
| F Patch | -0.012 |
| G Patch | -0.259 |
| H Patch | -0.077 |
| I Patch | -0.011 |
| K Patch | -0.253 |
| L Patch | -0.096 |
| M Patch | -0.026 |
| N Patch | -0.076 |
| P Patch | -0.447 |
| Q Patch | -0.160 |
| R Patch | -0.247 |
| S Patch | -0.025 |
| T Patch | -0.147 |
| V Patch | -0.051 |
| Y Patch | -0.022 |
| RG Frac | -0.130 |
IDR 2
Cluster 6
Residues 1212–1255 · 43 aa
(3.4% of protein) · Min inter-cluster distance: 2.907
S patches
Sequence
HTHGRYVPPSSTDRSPYEKVSAGNGGSSLSYTNPAVAATSANL
Top exceptional features (|z-score| rank)
Frac Y: +3.52A Patch: +2.99Frac Chain Expanding: -1.74hyd-hyd: -1.55Frac Aromatic: +1.48ala-ala: +1.45FCR: -1.31Frac N: +1.25
Show all 90 sequence-feature z-scores
| Feature | Z-score |
|---|
| pol-pol | +0.374 |
| pol-hyd | -0.831 |
| pol-pos | +0.000 |
| pol-neg | +0.000 |
| pol-aro | +0.000 |
| pol-ala | +0.019 |
| pol-pro | +0.000 |
| pol-gly | +0.000 |
| hyd-hyd | -1.551 |
| hyd-pos | +0.000 |
| hyd-neg | +0.000 |
| hyd-aro | +0.000 |
| hyd-ala | -0.567 |
| hyd-pro | +0.000 |
| hyd-gly | +0.000 |
| pos-pos | +0.000 |
| pos-neg | +0.000 |
| pos-aro | +0.000 |
| pos-ala | +0.000 |
| pos-pro | +0.000 |
| pos-gly | +0.000 |
| neg-neg | +0.000 |
| neg-aro | +0.000 |
| neg-ala | +0.000 |
| neg-pro | +0.000 |
| neg-gly | +0.000 |
| aro-aro | +0.000 |
| aro-ala | +0.000 |
| aro-pro | +0.000 |
| aro-gly | +0.000 |
| ala-ala | +1.449 |
| ala-pro | +0.000 |
| ala-gly | +0.000 |
| pro-pro | +0.000 |
| pro-gly | +0.000 |
| gly-gly | +0.000 |
| Frac A | +0.713 |
| Frac C | -0.582 |
| Frac D | -0.675 |
| Frac E | -1.004 |
| Frac F | -0.807 |
| Frac G | +0.157 |
| Frac H | +0.852 |
| Frac I | -0.900 |
| Frac K | -0.670 |
| Frac L | -0.349 |
| Frac M | -0.832 |
| Frac N | +1.249 |
| Frac P | -0.284 |
| Frac Q | -1.207 |
| Frac R | -0.382 |
| Frac S | +0.914 |
| Frac T | +0.803 |
| Frac V | +1.238 |
| Frac W | -0.508 |
| Frac Y | +3.523 |
| Frac K+R | -0.754 |
| Frac D+E | -1.092 |
| Frac Polar | +1.040 |
| Frac Aliphatic | +0.433 |
| Frac Aromatic | +1.477 |
| R/K Ratio | +0.294 |
| E/D Ratio | -0.565 |
| Frac Chain Expanding | -1.739 |
| FCR | -1.315 |
| NCPR | +0.330 |
| Hydrophobicity | +0.924 |
| Disorder Promoting | -1.037 |
| Iso point | +0.670 |
| PPII | -1.045 |
| A Patch | +2.991 |
| C Patch | -0.009 |
| D Patch | -0.178 |
| E Patch | -0.349 |
| F Patch | -0.012 |
| G Patch | -0.259 |
| H Patch | -0.077 |
| I Patch | -0.011 |
| K Patch | -0.253 |
| L Patch | -0.096 |
| M Patch | -0.026 |
| N Patch | -0.076 |
| P Patch | -0.447 |
| Q Patch | -0.160 |
| R Patch | -0.247 |
| S Patch | -0.481 |
| T Patch | -0.147 |
| V Patch | -0.051 |
| Y Patch | -0.022 |
| RG Frac | -0.130 |