IDR 1
Cluster 13
Residues 145–291 · 146 aa
(50.2% of protein) · Min inter-cluster distance: 11.598
Blocks of negative, P, & polar residues
Note: this region spans the majority of the protein sequence, which may indicate a structured domain (e.g. a collagen triple helix or repetitive fibrous domain) that AlphaFold2 monomer predictions and sequence-based disorder predictors can misclassify as disordered. Interpret this grammar assignment with caution.
Sequence
NPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENNENSNSNSHNPLNGSGKSVLGSSEDEKTPSGTPDHSSSSPALLLSPPPPGLPSLHSLGHPPGPSAVPVPVPGGGGADPLQHHHGLQDSILNPMSANLVDLGS
Top exceptional features (|z-score| rank)
N Patch: +8.42neg-pro: +3.75pol-pol: +3.28pol-pro: +2.91pol-neg: +2.49hyd-neg: +2.01Frac N: +1.65pro-pro: +1.59
Show all 90 sequence-feature z-scores
| Feature | Z-score |
|---|
| pol-pol | +3.279 |
| pol-hyd | +1.238 |
| pol-pos | +0.000 |
| pol-neg | +2.492 |
| pol-aro | +0.000 |
| pol-ala | +0.000 |
| pol-pro | +2.913 |
| pol-gly | +0.000 |
| hyd-hyd | +1.298 |
| hyd-pos | +0.000 |
| hyd-neg | +2.011 |
| hyd-aro | +0.000 |
| hyd-ala | +0.000 |
| hyd-pro | +0.552 |
| hyd-gly | +0.000 |
| pos-pos | +0.000 |
| pos-neg | +0.000 |
| pos-aro | +0.000 |
| pos-ala | +0.000 |
| pos-pro | +0.000 |
| pos-gly | +0.000 |
| neg-neg | +1.458 |
| neg-aro | +0.000 |
| neg-ala | +0.000 |
| neg-pro | +3.751 |
| neg-gly | +0.000 |
| aro-aro | +0.000 |
| aro-ala | +0.000 |
| aro-pro | +0.000 |
| aro-gly | +0.000 |
| ala-ala | +0.000 |
| ala-pro | +0.000 |
| ala-gly | +0.000 |
| pro-pro | +1.589 |
| pro-gly | +0.000 |
| gly-gly | +0.000 |
| Frac A | -0.289 |
| Frac C | -0.582 |
| Frac D | -0.245 |
| Frac E | -0.427 |
| Frac F | -0.420 |
| Frac G | +0.203 |
| Frac H | +0.905 |
| Frac I | -0.555 |
| Frac K | -0.475 |
| Frac L | +1.262 |
| Frac M | -0.479 |
| Frac N | +1.647 |
| Frac P | +0.339 |
| Frac Q | -0.601 |
| Frac R | -0.354 |
| Frac S | +0.282 |
| Frac T | -0.362 |
| Frac V | +0.191 |
| Frac W | +0.115 |
| Frac Y | -0.203 |
| Frac K+R | -0.590 |
| Frac D+E | -0.445 |
| Frac Polar | +0.548 |
| Frac Aliphatic | +0.215 |
| Frac Aromatic | -0.357 |
| R/K Ratio | +0.170 |
| E/D Ratio | -0.090 |
| Frac Chain Expanding | -0.600 |
| FCR | -0.721 |
| NCPR | -0.052 |
| Hydrophobicity | +0.358 |
| Disorder Promoting | -1.117 |
| Iso point | -0.271 |
| PPII | -0.253 |
| A Patch | -0.265 |
| C Patch | -0.009 |
| D Patch | -0.178 |
| E Patch | +0.543 |
| F Patch | -0.012 |
| G Patch | +0.044 |
| H Patch | -0.077 |
| I Patch | -0.011 |
| K Patch | -0.253 |
| L Patch | -0.096 |
| M Patch | -0.026 |
| N Patch | +8.421 |
| P Patch | +0.084 |
| Q Patch | -0.160 |
| R Patch | +0.714 |
| S Patch | -0.172 |
| T Patch | +1.096 |
| V Patch | -0.051 |
| Y Patch | -0.022 |
| RG Frac | -0.130 |