NephVar / Molecular Grammars / SLC9A3R1

SLC9A3R1 NHRF1

USD panel · 358 aa · UniProt O14745 · 2 IDRs · View biophysical profile →
IDR map — colored by GIN molecular grammar cluster
IDR 1 Cluster 19
Residues 111–165 · 54 aa (15.1% of protein) · Min inter-cluster distance: 3.996
High negative fraction, specifically Es
Sequence
RAQEAPGQAEPPAAAEVQGAGNENEPREADKSHPEQRELRPRLCTMKKGPSGYG
Top exceptional features (|z-score| rank)
pos-ala: +1.91E/D Ratio: +1.44pro-pro: -1.34Frac S: -1.32Frac A: +1.30neg-pro: -1.11gly-gly: +1.05pol-neg: -0.98
Show all 90 sequence-feature z-scores
FeatureZ-score
pol-pol-0.838
pol-hyd+0.000
pol-pos-0.462
pol-neg-0.979
pol-aro+0.000
pol-ala+0.760
pol-pro-0.624
pol-gly-0.662
hyd-hyd+0.000
hyd-pos+0.000
hyd-neg+0.000
hyd-aro+0.000
hyd-ala+0.000
hyd-pro+0.000
hyd-gly+0.000
pos-pos+0.863
pos-neg-0.538
pos-aro+0.000
pos-ala+1.914
pos-pro-0.464
pos-gly+0.767
neg-neg-0.692
neg-aro+0.000
neg-ala-0.707
neg-pro-1.112
neg-gly+0.640
aro-aro+0.000
aro-ala+0.000
aro-pro+0.000
aro-gly+0.000
ala-ala+0.899
ala-pro-0.674
ala-gly+0.650
pro-pro-1.338
pro-gly-0.128
gly-gly+1.054
Frac A+1.298
Frac C+0.681
Frac D-0.789
Frac E+0.872
Frac F-0.807
Frac G+0.449
Frac H-0.172
Frac I-0.900
Frac K-0.096
Frac L-0.620
Frac M+0.121
Frac N+0.199
Frac P+0.235
Frac Q+0.433
Frac R+0.532
Frac S-1.319
Frac T-0.868
Frac V-0.634
Frac W-0.508
Frac Y+0.488
Frac K+R+0.283
Frac D+E+0.291
Frac Polar-0.668
Frac Aliphatic+0.265
Frac Aromatic-0.433
R/K Ratio+0.294
E/D Ratio+1.438
Frac Chain Expanding+0.640
FCR+0.404
NCPR-0.034
Hydrophobicity-0.718
Disorder Promoting+0.897
Iso point-0.406
PPII+0.586
A Patch-0.265
C Patch-0.009
D Patch-0.178
E Patch-0.349
F Patch-0.012
G Patch-0.259
H Patch-0.077
I Patch-0.011
K Patch-0.253
L Patch-0.096
M Patch-0.026
N Patch-0.076
P Patch-0.447
Q Patch-0.160
R Patch-0.247
S Patch-0.481
T Patch-0.147
V Patch-0.051
Y Patch-0.022
RG Frac-0.130
IDR 2 Cluster 25
Residues 249–358 · 109 aa (30.4% of protein) · Min inter-cluster distance: 3.844
Blocks of positive residues
Sequence
HLNGPLPVPFTNGEIQKENSREALAEAALESPRPALVRSASSDTSEELNSQDSPPKQDSTAPSSTSSSDPILDFNISLAMAKERAHQKRSSKRAPQMDWSKKNELFSNL
Top exceptional features (|z-score| rank)
pol-hyd: +1.69neg-neg: -1.69pol-pol: +1.52pos-pos: +1.50pol-ala: +1.28hyd-pos: +1.20hyd-ala: -1.16Frac N: +1.07
Show all 90 sequence-feature z-scores
FeatureZ-score
pol-pol+1.524
pol-hyd+1.689
pol-pos+0.787
pol-neg-0.920
pol-aro+0.000
pol-ala+1.277
pol-pro+0.000
pol-gly+0.000
hyd-hyd+0.527
hyd-pos+1.202
hyd-neg-0.771
hyd-aro+0.000
hyd-ala-1.160
hyd-pro+0.000
hyd-gly+0.000
pos-pos+1.505
pos-neg+0.290
pos-aro+0.000
pos-ala+0.373
pos-pro+0.000
pos-gly+0.000
neg-neg-1.689
neg-aro+0.000
neg-ala-0.488
neg-pro+0.000
neg-gly+0.000
aro-aro+0.000
aro-ala+0.000
aro-pro+0.000
aro-gly+0.000
ala-ala+0.886
ala-pro+0.000
ala-gly+0.000
pro-pro+0.000
pro-gly+0.000
gly-gly+0.000
Frac A+0.431
Frac C-0.582
Frac D+0.091
Frac E-0.113
Frac F+0.750
Frac G-1.051
Frac H-0.178
Frac I+0.487
Frac K+0.058
Frac L+0.947
Frac M+0.112
Frac N+1.071
Frac P-0.303
Frac Q-0.191
Frac R-0.213
Frac S+0.739
Frac T-0.460
Frac V-0.641
Frac W+0.327
Frac Y-0.609
Frac K+R-0.099
Frac D+E-0.043
Frac Polar-0.245
Frac Aliphatic+0.830
Frac Aromatic+0.245
R/K Ratio-0.274
E/D Ratio-0.090
Frac Chain Expanding-0.329
FCR-0.097
NCPR-0.033
Hydrophobicity+0.396
Disorder Promoting-1.056
Iso point-0.406
PPII-0.260
A Patch+0.836
C Patch-0.009
D Patch-0.178
E Patch-0.349
F Patch-0.012
G Patch-0.259
H Patch-0.077
I Patch-0.011
K Patch-0.253
L Patch-0.096
M Patch-0.026
N Patch-0.076
P Patch-0.447
Q Patch-0.160
R Patch-0.247
S Patch+0.866
T Patch-0.147
V Patch-0.051
Y Patch-0.022
RG Frac-0.130