NephVar / Molecular Grammars / SMARCAL1

SMARCAL1 SMAL1

SRNS panel · 954 aa · UniProt Q9NZC9 · 2 IDRs · View biophysical profile →
IDR map — colored by GIN molecular grammar cluster
IDR 1 Cluster 16
Residues 0–238 · 238 aa (24.9% of protein) · Min inter-cluster distance: 0.831
Blocks of polar residues
Sequence
MSLPLTEEQRKKIEENRQKALARRAEKLLAEQHQRTSSGTSIAGNPFQAKQGPSQNFPRESCKPVSHGVIFKQQNLSSSSNADQRPHDSHSFQAKGIWKKPEEMPTACPGHSPRSQMALTGISPPLAQSPPEVPKQQLLSYELGQGHAQASPEIRFTPFANPTHKPLAKPKSSQETPAHSSGQPPRDAKLEAKTAKASPSGQNISYIHSSSESVTPRTEGRLQQKSGSSVQKGVNSQK
Top exceptional features (|z-score| rank)
E/D Ratio: +1.36pol-pol: +1.28pol-pos: +1.21Frac Q: +1.03Frac D: -0.93hyd-pos: -0.86Iso point: +0.81Frac I: +0.79
Show all 90 sequence-feature z-scores
FeatureZ-score
pol-pol+1.280
pol-hyd+0.198
pol-pos+1.213
pol-neg+0.000
pol-aro+0.000
pol-ala+0.000
pol-pro+0.527
pol-gly+0.000
hyd-hyd-0.678
hyd-pos-0.865
hyd-neg+0.000
hyd-aro+0.000
hyd-ala+0.000
hyd-pro-0.367
hyd-gly+0.000
pos-pos-0.023
pos-neg+0.000
pos-aro+0.000
pos-ala+0.000
pos-pro-0.118
pos-gly+0.000
neg-neg+0.000
neg-aro+0.000
neg-ala+0.000
neg-pro+0.000
neg-gly+0.000
aro-aro+0.000
aro-ala+0.000
aro-pro+0.000
aro-gly+0.000
ala-ala+0.000
ala-pro+0.000
ala-gly+0.000
pro-pro-0.363
pro-gly+0.000
gly-gly+0.000
Frac A+0.121
Frac C-0.009
Frac D-0.931
Frac E-0.344
Frac F+0.619
Frac G-0.396
Frac H+0.534
Frac I+0.794
Frac K+0.409
Frac L+0.004
Frac M-0.183
Frac N+0.089
Frac P-0.114
Frac Q+1.026
Frac R-0.305
Frac S+0.267
Frac T-0.247
Frac V-0.390
Frac W-0.125
Frac Y-0.111
Frac K+R+0.102
Frac D+E-0.708
Frac Polar+0.451
Frac Aliphatic+0.135
Frac Aromatic+0.286
R/K Ratio-0.639
E/D Ratio+1.362
Frac Chain Expanding-0.626
FCR-0.466
NCPR+0.603
Hydrophobicity+0.127
Disorder Promoting-0.215
Iso point+0.805
PPII+0.162
A Patch-0.265
C Patch-0.009
D Patch-0.178
E Patch-0.349
F Patch-0.012
G Patch-0.259
H Patch-0.077
I Patch-0.011
K Patch-0.253
L Patch-0.096
M Patch-0.026
N Patch-0.076
P Patch-0.447
Q Patch-0.160
R Patch-0.247
S Patch-0.054
T Patch-0.147
V Patch-0.051
Y Patch-0.022
RG Frac-0.130
IDR 2 Cluster 3
Residues 898–943 · 45 aa (4.7% of protein) · Min inter-cluster distance: 4.914
Small negative blocks
Sequence
LLEAAESFDPGSASGTSGSSSQNMGDTLDESSLTASPQKKRRFEF
Top exceptional features (|z-score| rank)
Frac F: +2.96pol-neg: +2.56S Patch: +2.03PPII: -1.48Frac S: +1.46Frac Aromatic: +1.36neg-neg: +1.33Frac V: -1.31
Show all 90 sequence-feature z-scores
FeatureZ-score
pol-pol+0.767
pol-hyd+1.146
pol-pos+0.000
pol-neg+2.565
pol-aro+0.000
pol-ala+0.000
pol-pro+0.000
pol-gly+0.000
hyd-hyd-0.170
hyd-pos+0.000
hyd-neg-1.277
hyd-aro+0.000
hyd-ala+0.000
hyd-pro+0.000
hyd-gly+0.000
pos-pos+0.000
pos-neg+0.000
pos-aro+0.000
pos-ala+0.000
pos-pro+0.000
pos-gly+0.000
neg-neg+1.335
neg-aro+0.000
neg-ala+0.000
neg-pro+0.000
neg-gly+0.000
aro-aro+0.000
aro-ala+0.000
aro-pro+0.000
aro-gly+0.000
ala-ala+0.000
ala-pro+0.000
ala-gly+0.000
pro-pro+0.000
pro-gly+0.000
gly-gly+0.000
Frac A+0.211
Frac C-0.582
Frac D+0.370
Frac E-0.018
Frac F+2.963
Frac G+0.090
Frac H-0.849
Frac I-0.900
Frac K-0.294
Frac L+0.865
Frac M+0.312
Frac N-0.276
Frac P-0.973
Frac Q-0.223
Frac R-0.423
Frac S+1.457
Frac T+0.212
Frac V-1.311
Frac W-0.508
Frac Y-0.609
Frac K+R-0.501
Frac D+E+0.163
Frac Polar+0.608
Frac Aliphatic-0.098
Frac Aromatic+1.361
R/K Ratio-0.133
E/D Ratio-0.267
Frac Chain Expanding-0.934
FCR-0.205
NCPR-0.453
Hydrophobicity+0.731
Disorder Promoting-0.034
Iso point-1.011
PPII-1.481
A Patch-0.265
C Patch-0.009
D Patch-0.178
E Patch-0.349
F Patch-0.012
G Patch-0.259
H Patch-0.077
I Patch-0.011
K Patch-0.253
L Patch-0.096
M Patch-0.026
N Patch-0.076
P Patch-0.447
Q Patch-0.160
R Patch-0.247
S Patch+2.030
T Patch-0.147
V Patch-0.051
Y Patch-0.022
RG Frac-0.130